NIIOS Research & Development conducts ophthalmic research and develops tissue preparation methods and surgical techniques with a focus on advanced lamellar keratoplasty. NIIOS R&D works closely with NIIOS (Netherlands Institute for Innovative Ocular Surgery).

New Concepts

Developing a new surgical protocol encompasses more than just the operation itself. We also look at new ways to harvest and prepare donor tissue and to develop new surgical instruments and medical devices. We closely monitor and evaluate clinical outcomes of procedures such as (advanced) DMEK (Descemet membrane endothelial keratoplasty) and Bowman layer transplantation in order to continually improve and refine these techniques.


At NIIOS R&D, we work closely with Melles Cornea Clinic and Amnitrans EyeBank. That collaboration makes it easier to approach topics from multiple angles and to find innovative solutions. It also speeds our ability to see what further work needs to be done. This approach has produced innovations such as the SurgiCube® and the staining solutions MembraneBlue Dual® and Vision Blue®.

Read more about our ongoing projects and completed projects.